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“Our goal is to know female reproductive aging, and why fertility quickly declines starting within the mid-30s,” suggests Satoshi Namekawa, a professor of Microbiology and Molecular Genetics, in whose lab Munakata will work.
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This allows the oocytes to pause their development and enter a Keeping pattern, which lasts in to the mouse’s adulthood. In mice lacking PRC1, the oocytes didn’t pause their advancement; in its place, they withered and died inside a month, leaving the mice completely infertile.
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“We don’t know the way these cells are preserved for many years,” states Namekawa. “We need to know the secret of this system.
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